Large Segmental Nevus Spilus Associated With Congenital Spondylolysis

[Smooth muscle hamartoma associated with acquired Blaschkoid nevus spilus].

Smooth muscle hamartoma (SMH), described by Stokes in 1923, is a proliferation of smooth muscle bundles. It can be single or multiple and may be congenital and acquired.1 The most frequent presentation is the localized congenital form, which is characterized by a plaque with a variable degree of hyperpigmentation, hypertrichosis, and induration. It is usually less than 10 cm in diameter and app...

Treatment of nevus spilus with CO2 Laser

Background: Nevus spilus can produce considerable disfigurement. There is no specific and successful treatment for this nevus. Objective: The purpose of this study was to evaluate the efficacy of CO2 laser in the treatment of nevus spilus. Patients and Methods: This quasi-experimental clinical trial was performed on 47 patients with spilus nevus in Al-Zahra Hospital in Isfahan. The diagnosis of...

Large congenital nevus spilus—improved follow-up through the use of in vivo reflectance confocal microscopy

BACKGROUND Nevus spilus (NS) is a potential precursor of melanoma; the vast majority of cases reported in the literature were histologically classified as superficial spreading melanoma. OBJECTIVE To demonstrate the diagnostic value of reflectance confocal microscopy (RCM) in this subtype of congenital nevi. METHODS We report a case of a large congenital NS with equivocal clinical and dermo...

Nevus Spilus: A Review of the Literature

Synchronous melanomas arising within nevus spilus*

Nevus spilus is a melanocytic cutaneous lesion consisting of a light brown background macule with numerous superimposed darker maculopapular speckles. Melanoma arising from a nevus spilus is rare, with less than 40 cases reported to date. The absolute risk for malignant transformation is not well defined, lacking a standardized management approach. We report a new case of melanoma arising from ...